Panthenol - a soothing moisturizer

Panthenol, also known as pro-vitamin B5, is a well-known active ingredient that is often found in pharmacy products, especially in wound-healing ointments. This active ingredient is well absorbed by the skin when applied externally and is enzymatically converted into pantothenic acid (Vitamin B5) in the body.

Vitamin B5 is an essential component of coenzyme A, which is involved in various physiological processes, such as intracellular fat synthesis in the skin. Compared to vitamin B5, panthenol penetrates the skin better and shows excellent compatibility. It has skin-caring and moisturizing properties, strengthens the skin's barrier function, and compensates for reduced hydration in dry skin. This is achieved by increasing the water content and positively influencing the molecular mobility of the lipid lamellae and proteins of the stratum corneum, which in turn reduces transepidermal water loss.

Panthenol is not only used in wound healing ointments to support wound healing in burns, scalds, corneal lesions, and allergic dermatitis in all three phases, but it also has a protective effect against skin irritations.

Panthenol finds diverse applications in cosmetics, and its positive effect on skin health makes it a highly valued ingredient. Due to its very good tolerability and low tendency to cause allergic reactions, panthenol is suitable for a wide range of skin types. Overall, panthenol is an effective ingredient that helps to care for, soothe, and moisturize the skin. Therefore, when choosing skincare products, it is advisable to look for panthenol as one of the key ingredients to benefit from the numerous advantages of this active substance.

Panthenol is found in our products at 5% with wound-healing properties in the Better Balm Ceramide Lip Care as well as in the Hypnotic Hues Nourishing Lip Tint.

Sources

Zhu J.,Wang Y. F.,Song S. S.,Wu L. L.,Chen Y.,Li X. Y.,Ju M. (2023). Alleviating skin barrier disruption, skin inflammation, and Pruritus: a moisturising spray with β-glucan and panthenol. International Journal of Dermatology and Venereology, 6(01), 1-8.

Proksch E, de Bony R, Trapp S, et al. Topical use of dexpanthenol: a 70th anniversary article. J Dermatolog Treat 2017;28(8), 766-773.

Scott LN, Fiume M, Bergfeld WF, et al. Safety assessment of panthenol, pantothenic acid and derivatives as used in cosmetics. International Journal of Toxicology. 2022;41(3), 77-128.

Camargo Jr F. B.,Gaspar L. R.,Maia Campos P. M. (2011). Skin moisturizing effects of panthenol-based formulations. Journal of cosmetic science, 62(4), 361.

Gorski J.,Proksch E.,Baron J. M.,Schmid D.,Zhang L. (2020). Dexpanthenol in wound healing after medical and cosmetic interventions (post procedure wound healing). Pharmazeutika, 13(7), 138.

Baron J. M.,Glatz M.,Proksch E. (2020). Optimum support of wound healing: new insights. Dermatology, 236(6), 593-600.