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AMINO ACIDS

Amino acids such as alanine, arginine, isoleucine, valine, proline, threonine, glycine, serine, histidine, phenylalanine, aspartic acid as well as the derivatives sodium PCA and PCA help maintain the water balance in the outermost layer of the skin. (1) As natural moisturizing factors (NMF) of the skin, they simultaneously support the maintenance of the skin's protective barrier. (2) The amino acids and their derivatives absorb moisture from the environment and store it in the lipid-protected corneocytes of the skin. In combination with lipids that slow down water diffusion, amino acids help corneocytes maintain their normal flattened, elongated shape, in which they can selectively bind and retain water. (3)

(1) Oshimura, E. (2017). Cosmetic Science and Technology || Amino Acids, Peptides and Proteins. , (), 285–303.

(2) Ohnari, H.,Sekiya, M.,Naru, E.,Ogura, T.,Sakata, O.,& Obata, Y. (2021). Amino acids and their N-acetylated derivatives maintain the skin's barrier function. Chemical & pharmaceutical bulletin, 69(7), 652–660.

(3) Lodén, Marie; Maibach, Howard I. (2012). Treatment of dry skin syndrome || Impact of stratum corneum damage on the natural moisturising factor (NMF) in the skin. , 10.1007/978-3-642-27606-4(Chapter 29), 441–451.