PALMITOYL TETRAPEPTIDE-7

Palmitoyl-Tetrapeptide-7 is a component of certain antibodies with the sequence Pal-Gly-Gln-Pro-Arg.1Together with Palmitoyl Tripeptide-1, it is also known as Matrixyl™3000. In studies, Matrixyl™3000 was shown to lead to a statistically significant reduction in wrinkle length and depth, as well as skin roughness, and an increase in skin thickness. (1)

Palmitoyl tetrapeptide reduces the release of a pro-inflammatory signaling protein and thus reduces inflammation after UVB exposure. (2) (3)

(1) Schagen, S. (2017). Topical Peptide Treatments with Effective Anti-Aging Results. Kosmetik, 4(2), 16.

(2) Resende, D. I. S. P.,Ferreira, M. S.,Sousa-Lobo, J. M.,Sousa, E.,& Almeida, I. F. (2021). Usage of synthetic peptides in cosmetics for sensitive skin. Pharmaceuticals (Basel, Switzerland), 14(8), 702.

(3) Mondon, P.;Hillion, M.;Peschard, O.;Andre, N.;Marchand, T.;Doridot, E.;Feuilloley, M.G.;Pionneau, C.;Chardonnet, S. Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: Effect of age and peptide applications. J. Cosmet. Dermatol. 2015, 14, 152–160.