ASCORBYL TETRAISOPALMITATE

Ascorbyl Tetraisopalmitate is a vitamin C derivative and is used in cosmetics for its antioxidant properties to prevent skin aging. (1) 

It has a high affinity for the stratum corneum of human skin and is also capable of promoting collagen synthesis in the deeper cells. (2,3)

In a 2021 study, it was able to increase skin moisture, reduce hyperpigmentation, and promote cell renewal of the epidermis in combination with other substances such as rice peptides. (4)

(1) Almeida, M.,Lima, C., Quenca-Guillen, J.,Son, E., Mercuri, L., Santoro, M., & Kedor-Hackmann, É. (2010). Stability evaluation of tocopheryl acetate and ascorbyl tetraisopalmitate in isolation and incorporated into cosmetic formulations using thermal analysis. Brazilian Journal of Pharmaceutical Sciences, 46, 129-134.

(2) Machado, N., Santos, L., Carvalho, B., Singh, P., Soto, C., Azoia, N., Cavaco‐Paulo, A., Martin, A., & Fávero, P. (2016). Assessment of penetration of Ascorbyl Tetraisopalmitate into biological membranes by molecular dynamics. Computers in biology and medicine, 75, 151-9.

(3) Dulińska-Molak, I., Pasikowska-Piwko, M., Dȩbowska, R., Świȩszkowski, W., Rogiewicz, K., & Eris, I. (2019). Determining the effectiveness of vitamin C in skin care by atomic force microscope. Microscopy research and Technique, 82, 1430-1437.