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SUPEROXIDE DISMUTASE (SOD)

Superoxide Dismutase (SOD) is an antioxidant enzyme used in skincare to combat oxidative stress, reduce premature skin aging, and protect against environmental damage (including UV radiation). It plays a crucial role in protecting cells from oxidative stress, as it catalyzes the dismutation of superoxide radicals (O2-) into oxygen and hydrogen peroxide. SOD represents a cell protection mechanism as it protects the cells from DNA, protein, and lipid damage. (1, 2)

Together with Glycine Soya Protein and Hydrolyzed Rice Protein, Superoxide Dismutase was able to improve skin texture in an in-vivo study, as well as enhance capillary circulation and stimulate fibroblast proliferation in vitro. (3)


(1) Islam, M., Rauf, A., Fahad, F., Emran, T.,Mitra, S., Olatunde, A., Shariati, M., Rebezov, M., Rengasamy, K., & Mubarak, M. (2021). Superoxide dismutase: an updated review on its health benefits and industrial applications. Critical Reviews in Food Science and Nutrition, 62, 7282-7300.

(2) Palmieri, G., Arciello, S., Bimonte, M., Carola, A., Tito, A., Gogliettino, M., Cocca, E., Fusco, C., Balestrieri, M., Colucci, M., & Apone, F. (2019). The extraordinary resistance to UV radiations of a manganese superoxide dismutase fof Deinococcus radiodurans offers promising potentialities in skin care applications. Journal of biotechnology.

(3) Manufacturer study